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For type 2 diabetes, the typical starting dose is 500 mg once or twice daily with meals, gradually increased based on glycemic response and tolerance
One final point before we move on to questions and answers
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Weight reduction amplifies these effects, as even a 510% reduction in body weight can meaningfully decrease cardiovascular strain and improve heart function
Furthermore, the authors noted than more than 80 percent had been on the lower dosages needed to sustain a therapeutic effect
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