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Itching, burning, irritation, painful intimacy, and shifts in discharge can linger for months or even years

Officioso A, Alzoubi K, Manna C, Lang F

Continuous use advantages include maintaining peak benefits without decline periods, avoiding the uncertainty of whether improvements will persist after breaks, simplifying routine through consistency, and potentially maximizing cumulative collagen synthesis through sustained stimulation over months to years

In contrast, TBC1D15 levels decreased in both NPC1 patient fibroblast lines compared to control (Supplementary Fig

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doi: 10.1073/pnas.85.10.3653