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In preclinical research models, MT-2 has been characterized for its agonism at MC1R (the receptor governing melanocyte eumelanin synthesis) and at MC4R (a central receptor studied in energy-homeostasis and melanocortin-signaling research)

[6] [7] [8] In selenoproteins, the 21st amino acid selenocysteine is inserted in the nascent polypeptide chain during the process of translational recoding of the UGA stop codon

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