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Interestingly, astrocytes often do not transition into this more damaging/senescent-like state unless microglia induce the switch through the release of cytokines like IL-1 and TNF (Herx et al., 2000
Some of the best known examples are Wegovy and Ozempic, but there are a few other GLP-1 options on the market, such as: Zepbound Mounjaro Trulicity Rybelsus Saxenda Victosa Byetta GLP-1 drugs typically come as injections (the exception is Rybelsus, which is in pill form)
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