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Causes and considerations: Direct taste sensation from the copper-containing complex Post-nasal drip from nasal formulations Transient effect often mitigated with delivery technique adjustments The metallic taste is not typically a clinically meaningful adverse effect, but it can be bothersome enough that patients discontinue therapy

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Neurologic symptoms, including developmental delays, cognitive disorders, and seizures, have also been observed (185, 186)

[11] [3] This is the rate limiting step

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