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Rebolledo-Solleiro D, Crespo-Ramrez M, Roldn-Roldn G, Hiriart M, de la Mora MP
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Multiple validated approaches exist, with selection depending on specific goals, injury characteristics, and individual response patterns
In particular, the initial burst of superoxide that cannot be eliminated efficiently due to the inactivity of SOD1 is promptly buffered by the induction of GSH synthesis resulting in protection against oxidative stress and cell death
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