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In patients considered low risk for progressionbased on factors such as imaging findingsit may be reasonable to explore alternative strategies

The cascade of events causing liver injury begins with the physiological dietary intake and intestinal absorption of copper, which cannot be adequately managed by patients with Wilson disease, ultimately resulting in severe copper dysregulation

In summary, tirzepatide achieved more pronounced HbA1c reductions with a lower incidence of hypoglycemia at week 52 compared to insulin glargine

No published controlled human trial was identified for this article

doi: 10.1016/j.pcl.2015.08.008 25 BernasconiSLevyCCohenRGiardinoIPettoello-MantovaniMSomekhE

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