P 18 mm and peak endometrial thickness in PCOS women (Reference Maged, Elsawah and Abdelhafez8)
This is an order of magnitude higher than small molecules, which average 168 to 308 kg of input per kilogram of API, and even above many biologics that hover around 8,300 kilograms of input per kilogram of API
, 133 , 144-152, doi: Larraufie, M
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[10] [11] Whilst these medications have proven benefits for glycaemic control and weight loss, their effects on gastrointestinal function mean they can influence digestive symptoms, which is particularly relevant for individuals with pre-existing bowel conditions such as IBS