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Additionally, if the dose remains subtherapeutic for an individual's physiology, the expected appetite reduction may not materialise

Pfeiffer, D

Avoiding meals right before bedtime is beneficial to manage heartburn, especially by avoiding eating three hours before you go to sleep

Rare but serious risks include pancreatitis, gallbladder problems, and thyroid C-cell tumors (observed in animal studies, clinical significance in humans unclear)

However, most people only experience unwanted semaglutide side effects for the first few weeks of treatment

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