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Pharmaceutics 12 (5), 440
For weight loss, current head-to-head evidence at obesity-treatment doses favors tirzepatide over semaglutide on average
Similarly, tryptamine, derived from bacterial tryptophan metabolism, activates mucosal 5-HT4 receptors, enhancing peristaltic reflexes ( Altered microbial composition or reduced fermentation capacity can impair this endocrine-neural interface of motility control
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