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At the primary endpoints, the rate of NASH resolution and the rate of improvement in NAFLD activity score and fibrosis of each group from baseline (pre-test) at 52 weeks of treatment will be calculated, and comparisons between groups will be performed using the CochranMantelHaenszel test, with adjustments for background factors, such as fibrosis stage (13, 4) and NAS (46, 78), at a 5% significance level (two-sided)
However, there are caveats
[15] [16] The effects on tolerability with extended dosing intervals have not been systematically studied
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Always consult with your healthcare provider before starting any new treatments if you are pregnant or breastfeeding.
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