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It works as an alpha-2 adrenergic agonist, meaning it blocks nerve signals that cause muscles to contract

However, findings in a systematic review and meta-analysis of prolonged NSAID use (ranging from one to seven years) indicated NSAIDs accelerate OA progression

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Retatrutide may influence processes related to hunger, satiety, blood sugar regulation, energy balance, and metabolism through GLP-1, GIP, and glucagon signaling pathways

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