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Device-based measurement showed that higher light-intensity physical activity and more daily steps were associated with significantly lower risk of these outcomes, independent of moderate- to vigorous-intensity physical activity and prepregnancy body mass index

Therefore, it is possible that this GLP-1 receptor agonist produces a bronchorelaxant effect on human airway smooth muscle, allowing possible reduction of certain agents (beta-agonists) or synergistic with other agents such as antimuscarinic drugs

Key points Incretins have an important role in glucose homeostasis, regulation of appetite, energy expenditure and immunity

However, we must interpret these findings with caution, explicitly acknowledging the significant heterogeneity in study design, patient cohorts, and choice of comparator agents that characterizes the current body of literature

Its distinct mode of action keeps drawing a lot of attention for additional study

Patients with prior thrombosis, thrombophilia, or cancer require individualized risk assessment and may benefit from additional monitoring or alternative therapy