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Some amount of ROS is critical for normal T cell survival and maturation, and appropriate physiologic upregulation of ROS levels is needed for T cell receptor activation and downstream signaling that leads to T helper cell type 1 (Th1) differentiation and production of pro-inflammatory cytokines, such as IFN- and TNF- (63)

Iyanda A, Anetor J, Adeniyi F, et al

doi: 10.1007/s11356-016-8048-4 20 BhantanaP.RanaM

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We also dig into the history, from ancient Greek bloodletting to George Washington's death to John Harvey Kellogg's yogurt enemas (ew?) and the psychology of why we fall for purity narratives