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Planimetry method was used to quantify wound area on Days 0, 7, 14, and 21

Dysbiosis reduces SCFA levels (e.g., butyrate), weakening antioxidant defenses and neuroprotection

Although we have outlined recent insights of cGAS-STING in regulating IFN, inflammation, oxidative stress, autophagy and endoplasmic reticulum stress upon virus infections, this signalling axis is also involved in some other early host antiviral processes, such as different types of cell death and metabolism ( Figure 3 )