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Patients with peripheral arterial diseases who develop claudication have significant impairments when performing physical exercises and have difficulty walking even at short distances at slow speeds

This can lead to weight gain and other health problems, like type 2 diabetes

Zofran is very effective in treating this

The article points to patients with significant nausea or vomiting early in treatment, who it says show higher rates of temperature dysregulation

Regulation and research are still evolving