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We did expect some degree of positive findings, but the extent to which these findings were positive in our study was a little bit surprising, Sheth told Healio

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[3] Afamelanotide was also found to sometimes induce darkening of certain pre-existing skin conditions, so regular full body skin examinations every 6 months is often recommended

Third, we examined a broad spectrum of clinically relevant SUD outcomes including AUD, OUD, NUD, and CUD, allowing assessment of consistency across substances and supporting the possibility of a class effect