In fact, weight loss due to a major decline in lean body mass is normally associated with a decline in skeletal muscle mass and strength, resulting in an increased risk of sarcopenia, impaired glucose sensitivity, and poor glucose control ( The liver plays a central role in the regulation of lipid metabolism as it is the foremost site of lipid uptake, synthesis, oxidation, and distribution to peripheral tissues
Conflicts of Interest There are no conflicts of interest
- Seek medical care if you experience severe or persistent pain in your abdomen, chest pain, or continuous vomiting or diarrhea
Should You Taper Off Tirzepatide
Combining them can cause dangerously shallow breathing, extreme sleepiness, and can be fatal
doi: 10.3389/fphar.2025.1610793 Received 12 April 2025 Accepted 21 July 2025 Published 18 August 2025 Volume 16 - 2025 Edited by Michael Heinrich, University College London, United Kingdom Reviewed by Sena Ardicli, Bursa Uluda University, Trkiye Huiwen Pang, University of Queensland, Australia Updates Copyright 2025 Zedan, El-Moslemany, Bahnasy, Eldamaty, Ibraheim, Alotaibi, Abdelmegeid, Shukry and Elolimy