It does not significantly affect appetite, body weight, or the incretin system
48-week clinical data: ~21% body weight reduction #1: Retatrutide The first triple-agonist, activating GLP-1, GIP, and glucagon receptors
Tsukiyama K, Yamada Y, Yamada C, et al
They were the primary supply source during the shortage era
Telehealth Providers offering FDA-Approved Medications Stick With FDA-Approved GLP-1s With the FDA officially banning compounded semaglutide and tirzepatide, the safest and most legal path forward is to stick with name-brand GLP-1 medications like Ozempic, Wegovy, Zepbound and Mounjaro
Medications such as Wegovy or Zepbound should not be used in people with a personal or family history of medullary thyroid cancer