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Tambin importa la tolerancia digestiva

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By lowering plasma glucose through renal excretion and modestly increasing circulating ketone availability, SGLT2 inhibitors shift systemic and cerebral energy metabolism away from exclusive dependence on glucose [27]

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Tamoxifen-inducible cellspecific Glp-1r KO (MIP-Cre-hGlp-1r) mice were generated in-house from our colony

The compound functions as a selective ghrelin receptor (GHS-R1a) agonist, demonstrating high binding affinity and activation specificity compared to other growth hormone releasing peptides