Add to that an environment filled with ultraprocessed foods, oversized portions, high stress and limited time for movement, and it's no surprise that so many people's weight ends up yo-yoing despite their best efforts
Is that risk big enough that should factor into the conversation about whether these drugs would be useful to the individual
doi: 10.1159/000119325 31 VermeulenRScholteH
Int J Reprod Biomed 21:99110 Salehpour S, Nazari L, Hoseini S, Bameni MP, Gachkar L (2019) Effects of LC on PCOS
The problem is that most of it requires effort yet another capsule to remember, another powder to mix, another twenty-minute routine to squeeze into a morning that's already scheduled down to the minute
Interestingly, a coronatine-deficient mutant bacterium caused only mild symptoms but consistently induced 2- to 5-times higher GST transcript levels than the coronatine-producing wild type strain