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The mutualistic fungus Piriformospora indica protects barley roots from a loss of antioxidant capacity caused by the necrotrophic pathogen Fusarium culmorum

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In this sense, MOTS-c works as an endogenous exercise mimetic, triggering AMPK activation through the same molecular lever that exercise pulls, just from the inside [1]

However, post-cholecystectomy patients may experience overlapping digestive symptoms

Macrophage-inducible C-type lectin (Mincle) can activate KCs through recognizing a damaged hepatocyte releasing endogenous ligand, named spliceosome-associated protein 130 (SAP130), to exacerbate APAP hepatotoxicity