This series of phase 3, randomised, double-blind, placebo-controlled clinical trials involved more than 25,000 individuals with overweight or obesity and has extensively demonstrated the efficacy of once-weekly subcutaneous semaglutide 2.4 mg in promoting weight loss [13, 38,39,40,41,42,43,44,45,46]
Bernardi, P
Implications for marketers: Interest in GLP-1s is highest among consumers diagnosed as overweight or obese, but weight loss isnt always what motivates people to use GLP-1s
Randomized trials focused on efficacy and common adverse events but were not powered to detect rare thromboembolic events reliably
Clinical experience suggests the combination may enhance weight loss for some patients
The medication is typically shipped directly to their health-care providers office for dispensing