Determining the true incidence of gastroparesis associated with GLP-1 receptor agonist use presents significant methodologic challenges
InThought: Both SERDs are poised to establish a new endocrine backbone in HR+/HER2- breast cancer, shifting treatment toward combination therapies and broader applicability
Compounded semaglutide products are not FDA-approved finished drugs and have not been independently evaluated by the FDA for safety, effectiveness, or quality
This increased activity puts immense strain on those delicate peptide bonds
NICE NG28 emphasises that HbA1c targets should be individualised, taking into account patient preferences, comorbidities, and risk of hypoglycaemia, rather than applying a single universal threshold
Common side effects include nausea, vomiting, diarrhoea, constipation, and abdominal discomfort, which are generally mild to moderate and tend to diminish over time