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ATP depletion stimulates PKC-alpha activity and leads to translocation of the enzyme to the plasma membrane, thereby enhancing serine phosphorylation of membrane proteins, such as the Ca 2+ -permeable cation channel (Fig

Cells were fixed with 4% paraformaldehyde in PBS for 15 min

Applying offline fractionation lead to an average increase in found proteins at 1% FDR of 23.7% and 28.5% for RLM and Supersomes incubated samples, respectively

The effects of steroid hormones can also vary depending on the microenvironment and disease-state

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DNA damage induced by free radicals includes base modifications, strand breaks, and cross-linking