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For example, confirming the microbial origin of a metabolite requires in vitro culturing of microorganisms isolated from the faeces followed by looking for the desired compounds in the appropriate microbial extracts (Puig-Castellv et al., 2023)

Seungpyo Hong and Ryan Pearson for helpful discussions of experiments for this manuscript

Lean mass includes muscle, water, connective tissue, and other non-fat tissue

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The cancers included in the study were gallbladder, colorectal, ovarian, endometrial, kidney, esophageal, liver, multiple myeloma, meningioma and pancreatic cancerswhich are all obesity-related cancers

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