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developmental code PNB-0408) is a synthetic small oligopeptide derived from angiotensin IV (AngIV), engineered to overcome AngIVs limitations as a research tool by adding lipophilic modifications that confer oral bioavailability and blood-brain barrier permeability

Immunohistochemical staining demonstrated partial Cyclin D1 expression, supporting functional activation of the MAPK pathway, whereas no mTOR staining was observed (Figures 2F,G), consistent with the epigenetic findings

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