Key Points: Life Biosciences, a biotech company co-founded by Harvards David Sinclair, received the FDAs permission to start a clinical trial of a gene therapy designed to rejuvenate dying cells
The overlap is almost complete
Another noted that results were inconsistent between shipments, suggesting possible batch-to-batch variation
Most treatment discontinuations were due to gastrointestinal AE and occurred during the rapid escalation phase this may be mitigated with more gradual dose escalation at phase 3 trials
These medications work by binding to GLP-1 receptors located throughout the body, including the pancreas, brain, and gastrointestinal tract, with indirect effects on the liver
Archived from the original on 9 January 2015