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Main menu Common skin conditions NEWS Join DermNet PRO Read more Quick links Author: Dr Mark Duffill, Dermatologist, Hamilton, New Zealand, 2008
CJC-1295 is not merely "not approved"
Buffoni F, Pino R, Dal Pozzo A
Molecular Identity Full Name Body Protection Compound 157 Structure Pentadecapeptide (15 amino acids) Sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val Molecular Weight ~1419 g/mol Origin Synthetic fragment derived from human gastric juice protein Mechanism of Action Published research identifies several pathways through which BPC-157 may affect tissue: Angiogenesis promotion: Studies show BPC-157 promotes blood vessel formation in animal models (Seiwerth et al., 2018) Nitric oxide system modulation: Interactions with NO pathways have been documented Growth factor activity: Research indicates effects on VEGF and EGF pathways FAK-paxillin pathway: Cell migration studies show activation of focal adhesion kinase Published Research Study Focus Model Publication Seiwerth et al
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