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SOURCE: Trujillo JM, Nuffer W, Smith BA
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It is notable that high spikes of blood insulin, (Hyperinsulinemia), initiates inflammation, which over times causes atherosclerosis and its sequela cardiovascular heart disease (CHD)
Emerging incretin-related therapies are under investigation for obesity and metabolic disorders including type 2 diabetes
Check the vial label for concentration (e.g., 5 mg/mL) Confirm U-100 syringe use as the use of other syringes can lead to errors Example: For 5 mg/mL, (2.5 5) 100 = 50 units Double-check with pharmacy instructions and rotate injection sites (abdomen, thigh, upper arm) weekly to prevent skin reactions Wipe the vial top and skin with an alcohol swab before every injection
It was suggested that this was achieved by inhibiting the production of pro-inflammatory cytokines and reducing the increase in intestinal permeability (102)
