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The critical difference is pharmacokinetic profile and the resulting GH secretion pattern

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In addition, recent studies suggest that GLP-1s may be linked with a rare yet serious condition called nonarteritic anterior ischemic optic neuropathy (NAION)

However, despite significant weight loss, liraglutide-treated animals displayed increased bone mass, trabecular number, and cortical thickness in the appendicular and axial skeletons, with marked improvement in bone formation parameters [55,56,57]

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