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The 3-year reduction in NT-proBNP was particularly noteworthy, with abnormal concentrations (125 ng/L) being recorded for 67.1% of participants receiving canagliflozin compared with 75.7% for placebo ( P =0.009)
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46,47,48 Overall, these outcome parameters might be too rough to capture potential adverse pulmonary effects of paracetamol, and more subtle outcomes, such as need for home oxygen or respiratory medication might be more informative
Cell migration was analysed by the ImageJ software
Some patients are instructed to gently pinch a fold of fatty tissue before inserting the needle
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