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Considering A2780 and A2780 cisR cells under hypoxia upon carboplatin exposure, cysteine was advantageous for A2780 cisR but not for A2780 parental cells, reinforcing that cysteine accounts for the selective process of platinum resistant ovarian cancer cells

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For between-group analyses, statistical significance was tested with an unpaired Students t -test

The GLP-1 receptor arm drives glucose-dependent insulin secretion alongside suppression of pancreatic alpha-cell glucagon output, slows gastric emptying, and engages central nervous system appetite-modulating circuits in the hypothalamus and brainstem (PMID 39515565)

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