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However, the FDA has not approved retatrutide for any indication

Medicaid coverage of GLP-1 receptor agonists for weight loss remains inconsistent nationwide, with approximately 40% of state programs covering these medications only for type 2 diabetes management rather than standalone weight reduction

Compared with metformin, which has shown fertility benefits and a mean weight loss of approximately 7 kg in some studies, GLP-1s often produce greater weight reduction and may yield higher pregnancy rates

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#Lupin #Pharma #GLP1 #Diabetes To view or add a comment, sign in From Gut Hormone to Wonder Drug - The Semaglutide Story: How One Molecule Rewired Obesity, Patents and Pharma Profits If you strip away the hype, semaglutide is essentially a clever copy of a natural hormone that signals to the body, Youve eaten enough. In the 1980s and 1990s, researchers discovered that the gut hormone GLP-1 could lower blood sugar, slow digestion, and curb appetite

It is also obtained from dietary sources, particularly red meat, with much smaller amounts in dairy and poultry