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Therapeutics and Clinical Risk Management, 21, 11871218

If the GI symptoms improve or resolve, then unnecessary studies and additional procedures may be avoided.

Nausea hit 45% of participants

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Lam CSP, Ramasundarahettige C, Branch KRH et al (2022) Efpeglenatide and clinical outcomes with and without concomitant sodium-glucose cotransporter-2 inhibition use in type 2 diabetes: exploratory analysis of the AMPLITUDE-O Trial

These pre-clinical data suggest unimolecular poly-pharmacology as an effective means to target multiple mechanisms contributing to obesity and further implicate GcgR activation as the differentiating factor between incretin receptor mono- or