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The most common cause of hypothyroidism in the UK is Hashimotos disease, an autoimmune disorder where the immune system attacks the thyroid gland

For type 2 diabetes, most guidelines recommend continuing metformin as foundational therapy

They are less likely to rely on authoritative sources of medical information and more likely to make risky medical choices based on opinions and experiences shared online

The risk is primarily driven by rapid weight loss and secondarily by direct GLP-1 receptor effects on gallbladder motility

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But here's what that two-decade timeline doesn't tell you: how these drugs actually work and why that mechanism matters more than the approval date