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Zhao F, Zhou Q, Cong Z, Hang K, Zou X, Zhang C, et al
Ozempic and Zepbound have different active ingredients (semaglutide vs
The increasing prevalence of obesity-related comorbidities such as diabetes, cardiovascular diseases, and hypertension has escalated the demand for more potent and targeted therapies, roles best fulfilled by prescription drugs
clinical evidence
A recent phase IIa, randomised, placebo-controlled trial enrolled 82 patients with biopsy confirmed NASH (NAS 4 with one point in each component, with fibrosis stage 1/2/3) with a minimum of 8% absolute liver fat content by MRI-PDFF and abnormal ALT (19 IU/L females, 30 IU/L in males)