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According to the company, people with obesity and knee osteoarthritis taking retatrutide lost up to 71 pounds on average, or nearly 30% of their baseline weight

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doi: 10.1016/J.METABOL.2021.154937 14 GiorginoFVoraJFeniciPSoliniA

Pregnancy and planned pregnancy are also contraindications, and patients should stop these medications well before any planned pregnancy

In the 12 subsequent days, food intake and body weight were measured daily, before the onset of the dark phase