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Structurally modified to contain 83 amino acids, IGF-1 LR3 has a significantly longer half-lifeapproximately 20 to 30 hourscompared to natural IGF-1, which typically lasts only 1215 minutes in circulation (Clemmons, Trends in Endocrinology & Metabolism )

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Mechanism of action, the amylin receptor complex Cagrilintide activates amylin receptors , these are special receptor complexes composed of two components