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Consider two key things to protect your muscles when losing weight on GLPs-1: 1) Eat protein at each meal (aiming for 1.21.6 g/kg/day is a common target), and 2) Do strength training 2 days per week

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Semaglutide/GLP-1 works by mimicking the GLP-1 hormone, which causes your body to produce more insulin, lowering your blood sugar levels and eventually signaling to the brain that you are full

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Massage (Optional) : Some people find gentle massage of the injection site helps distribute the medication, but its not required