That places BPC-157 in the same regulatory bucket as other unapproved research peptides like TB-500 (thymosin beta-4 fragment) and GHK-Cu
Alexion Pharmaceuticals, Inc
Yang C-C, Wang M-H, Soung H-S, Tseng H-C, Lin F-H, Chang K-C, et al
Henderson YC, Mohamed ASR, Maniakas A, Chen Y, Powell RT, Peng S, Cardenas M, Williams MD, Bell D, Zafereo ME , Wang RJ, Scherer SE, Wheeler DA, Cabanillas ME, Hofmann MC, Johnson FM, Stephan CC, Sandulache V, Lai SY
The peptide enhances TGF-beta receptor expression and increases cellular responsiveness to TGF-beta ligands, amplifying SMAD2/3 phosphorylation and nuclear translocation
Fischman were obtained from the Developmental Studies Hybridoma Bank developed under the auspices of the NICHD and maintained by The University of Iowa, Department of Biological Sciences, Iowa City, IA 52242, Iowa