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Only a small percentage of high-dose oral B12 is absorbed, which is why supplements are often formulated at much higher levels than the RDA. Cost Think about your budget before buying, and consider the likelihood that you may need to keep repurchasing this product

However, coverage is contingent upon the medical necessity as defined by the specific plan, which may vary

They are often studied together for a synergistic effect

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All statistical tests will be performed with intention to treat and per protocol