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IGF-I is harmonically produced by peaks that coincide with periods of neuron progenitor proliferation and differentiation, neuritic outgrowth (increasing the number of dendrites, axonal cones, synapse number) or post-injury conditions[59]

Cytokine storm and oxidative stress are the main participants in the development of ARDS during respiratory virus infections (Meftahi et al., 2021)

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This increases the bioavailability , meaning that a lower dosage is required