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Causes and Risk Factors of Insulin Resistance Obesity (defined as having a certain body mass index, or BMI) Eating a high-calorie, high-sugar diet Lack of physical activity Taking high doses of a steroid Chronic stress Having polycystic ovary syndrome (PCOS) or Cushings disease With a family history of type 2 diabetes With a personal history of gestational diabetes Over the age of 45 Who are Hispanic, African American, Native American, or Asian American With a waist circumference larger than 40 inches (men) or larger than 35 inches (women) With a history of high blood pressure (hypertension) or high triglycerides The risk factors for insulin resistance are similar to the risk factors for prediabetes and type 2 diabetes

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