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Serum triglycerides, HDL cholesterol, and the HOMA-index decreased throughout the follow-up, but these reductions never reached statistical significance ( Table 3 and Figure 4 )

Over time, consistent use under medical supervision can lead to significant and sustainable weight loss

Semaglutide trials showed an average weight loss of approximately 15%, indicating that the medication alters baseline physiology but typically requires ongoing support to sustain results

Nausea is the most frequently reported side effect, affecting 40 to 50 percent of patients at some point during treatment, typically during dose escalation

But I'm actually hopeful that we can use the current fervour around GLP-1 to re-educate the general public that obesity is a chronic medical condition

Cholesterol crystals and inflammation