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While tirzepatide has been investigated in type 1 diabetes contexts, its GLP-1 and GIP receptor agonism affects pancreatic function in ways that may interact unpredictably with pancreatic autoimmune processes

Patients report that their appetite and cravings are reduced all around. Read the whole article from Parade

doi: 10.3389/fphar.2022.836849 27 ManciniSJBoydDKatwanOJStrembitskaAAlmabroukTAKennedySet al

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But if the question extends to energy homeostasis, feeding behavior, or the interplay between GH and metabolic state, that appetite signal becomes the most valuable variable in the study