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Biochemical Journal , 467(2), 289301
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This review concluded that intakes up to 2 g/day are safe for chronic supplementation. An International Olympic Committee (IOC) statement on dietary supplements for high-performance athletes stated that No negative health effects are noted with long-term use of creatine
Overall, the risks of bias were relatively low for the whole included trials (See Figure 5 )
Several non-clinical and clinical research studies have investigated the influence of non-enzymatic, enzymatic, and natural antioxidants on preventing various diseases [21]
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