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10.1016/S0140-6736(18)32261-X 32 HolmanR
A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management (SCALE Obesity and Prediabetes)
Administration The medication is administered as a weekly subcutaneous injection into the abdominal area, similar to insulin injections
Importantly GLP-1 is brain penetrant 12 , as is liraglutide 13 , which is currently marketed for use in diabetic patients
Tirzepatide: Dual-Receptor Action Tirzepatide activates two receptors simultaneously: GLP-1 and GIP (glucose-dependent insulinotropic polypeptide)
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