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In a rat model of intervertebral disc degeneration, MOTS-c injection preserved disc height (82.4% versus 58.7% in the untreated group), restored MRI signals indicating improved disc hydration, and reduced histological degeneration scores by 44% compared to untreated controls

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It is not on the 503B outsourcing-facility list and has no USP/NF monograph, so it cannot legally be compounded by US pharmacies for human use