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The shift happens after patent protection ends

The site of administration should be decided and handled by a trained medical professional

The long-term sc administration of exendin-4 decreased daily food intake and practically blocked weight gain in obese rats
Di Cesare ML, Ghelardini C, Calvani M, et al
Am J Physiol Endocrinol Metab 303(1):E103E110 Hatoum IJ et al (2012) Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery

[2] [3] Monitor for signs of pancreatitis, gallbladder disease, and in patients with diabetes, potential retinopathy progression with rapid glycemic improvement

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